What is a stomach with a leather bottle and signet ring called?
A man wearing a Signet ring and drinking from a leather bottle would probably be a man from medieval era. However the same cannot be told about stomach having a leather bottle appearance and Signet ring cells . Such a stomach is said to be cancerous, most commonly of the adenocarcinoma type. In order to diagnose the diffuse type of adeno gastic carcinoma an endoscopy followed by microscopic examination of the sample are performed. During endoscopy the stomach looks like a leather bottle and under the microscope signet ring cells make an appearance. What could possibly be the reason behind these characteristic features? The leather bottle appearance is due to the thick and rigid stomach wall due to tumor infiltrating the submucosa. The Signet ring like appearance of the cells is due to mucin filled vacuoles pushing the nucleus to one side. (FYI - the other type of gastric Ca is the Intestinal type which has better prognosis and does not show the above m...
Comments
Post a Comment